Clinical, imaging and pathological findings of angiocentric gliomas: an analysis of 8 cases
10.3760/cma.j.issn.1671-8925.2015.09.002
- VernacularTitle:血管中心性胶质瘤八例临床、影像与病理学分析
- Author:
Chenxing WU
1
;
Zhengdong KONG
;
Kun YAO
;
Ning LIU
;
Xueling QI
;
Zhixiong LIN
Author Information
1. 首都医科大学三博脑科医院神经外科
- Keywords:
Angiocentric glioma;
Tumor histology;
Radiological imaging
- From:
Chinese Journal of Neuromedicine
2015;14(9):869-873
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical,imaging and pathological characteristics of angiocentric gliomas (AG) in Chinese patients,and provide opinions for diagnosis and treatment of the disease.Methods Eight patients with AG confirmed by histology in our hospital from January 1,2011 to March 31,2015,were chosen in our study;the clinical,imaging,and pathological data were retrospectively analyzed.Results In these 8 patients,one had onset of dizzy giddy and the other 7 had onset of epilepsy.T1-weighted imaging hypointense signal and T2-weighted imaging isointense or hyperintense signals were noted.CT scan showed calcification in 3 patients.Pathology indicated WHO grade Ⅰ-Ⅱ gliomas.Neoplastic cells were bipolar,round,oval or spindle shaped around capillary,and they expressed both glial markers (glial fibrillary acidic protein) and neuronal markers (neuronal nuclei antigen and synaptophysin).MR imaging showed that all the 8 patients got total resection,and follow up of 6-47 months recorded no epileptic seizure,neoplasm recurrence or death.Conclusions AG is a kind of low-grade glioma in children or young adults.And it may be a mixed neuronal-glial neoplasm originating from radial glia,enjoying good surgical effects.
