Treatment effect of excision via transoral-nosal-sphenoidal approach on pituitary adenoma and management of postoperative complications
10.3760/cma.j.issn.1671-8925.2015.07.014
- VernacularTitle:经鼻蝶窦入路垂体腺瘤切除术的疗效及术后并发症的防治
- Author:
Xiying QIAN
1
;
Weihua TAO
;
Jianhua ZHAO
;
Sunquan HONG
Author Information
1. 云南省第一人民医院神经外科
- Keywords:
Transoral-nosal-sphenoidal approach;
Pituitary adenoma;
Complication
- From:
Chinese Journal of Neuromedicine
2015;14(7):711-714
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the treatment effect of excision via transoral-nosal-sphenoidal approach on pituitary adenoma and management of postoperative complications.Methods One hundred and four pituitary adenoma patients,admitted to our hospital from January 2010 to December 2014 and microsurgically treated via transoral-nosal-sphenoidal approach,were chosen in our study.The clinical data of these patients and microsurgical treatment efficacy were analyzed retrospectively and postoperative complications were concluded.Results Total resection was observed in 82 patients (78.8％) and subtotal resection in 22 (21.2％).Forty-two patients got vision improvement with an improvement rate of 80.7％.Hormonal readiness recovered to normal level in 34 patients (44.7％);hormonal readiness being decreased but still higher than normal level was noted in 38 (50.0％).The major postoperative complications included diabetes insipidus,cerebrospinal fluid rhinorrhea,electrolyte disturbance,hypopituitarism and hemorrhage.The symptoms and signs of patients were improved in varied degrees,and the postoperative complications were controlled.Conclusions The transoral-nosal-sphenoidal approach is an ideal method to resect pituitary adenoma and active management of postoperative complications is essential to the prognosis of patients.
