Clinical features and risk factors of silent cerebral infarction: an analysis of 138 patients
10.3760/cma.j.issn.1671-8925.2015.07.002
- VernacularTitle:138例无症状性脑梗死患者临床特点及危险因素分析
- Author:
Yan SHI
1
;
Li GUO
;
Qingfan XIE
;
Fei WANG
;
Zhenyu YAN
;
Haixia CHEN
;
Runping WANG
Author Information
1. 河北医科大学第二医院神经内科
- Keywords:
Silent cerebral infarction;
Risk factor;
Clinical characteristic
- From:
Chinese Journal of Neuromedicine
2015;14(7):655-660
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical features,risk factors and gender differences of silent cerebral infarction (SCI),and provide the clinical basis for the primary and secondary preventions.Methods Three hundred and fifty-six patients without previous history of stroke and neurological signs,admitted to our hospital from January 2010 to January 2013,were selected and divided to 2 groups:an observation group (n=138,having SCI) and a control group (n=218,not having SCI).Age,gender,levels of blood pressure,blood glucose,triglyceride,low density lipoprotein (LDL) and total cholesterol,smoking history,drinking history,family history of stroke,and coronary heart disease history were analyzed by single and multiple factor Logistic analysis.SCI patients were divided into male SCI group and female SCI group to compare the differences of high risk factors.Results SCI lesions mainly located in the basal ganglia and crown areas of radiation,which were mainly multiple lesions.Logistic regression analysis showed that independent risk factors were age,hypertension,coronary heart disease history,diabetes history,high triglyceride and high LDL levels,and smoking history.The incidences of diabetes and coronary heart disease in female SCI patients were significantly higher than those in male SCI patients (P＜0.05),and those of high triglyceride and smoking in SCI female patients were statistically lower than those in male SCI patients (P＜0.05).Conclusion Risk factors of SCI include age,hypertension,coronary heart disease history,diabetes,high triglyceride and high LDL levels,and smoking;and gender differences exist in these risk factors.
