Treatment of cerebral venous sinus thrombosis associated with intracranial hematoma: a systematic review
10.3760/cma.j.issn.1671-8925.2015.06.010
- VernacularTitle:颅内静脉窦血栓形成合并颅内血肿的治疗方式的系统评价
- Author:
Xiaoyu KANG
1
;
Lijin HUANG
;
Jun WEN
;
Weijia HUANG
;
Xiaobin ZHANG
;
Honghua GUO
;
Shifeng DENG
Author Information
1. 南方医科大学第三附属医院神经外科
- Keywords:
Cerebral venous sinus thrombosis;
Intracranial hematoma;
Therapy method;
Systematic review
- From:
Chinese Journal of Neuromedicine
2015;14(6):586-590
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systemically evaluate the efficacy of all kinds of therapies of cerebral venous sinus thrombosis (CVST) associated with intracranial hematoma (ICH) and provide reference for making treatment scheme.Methods We searched English databases (Pubmed,ISI Web of science and Cochrane library databases) for publications on CVST associated with ICH and the relevant references of those articles.Retrieval time deadline was up to January 2015,and the language was set to English.All publications were searched without restrictions of publication type or published fields.Documents were screened to extract data and to analyze systemically.Results In total,17 articles fulfilled the inclusion criteria and included 31 patients.Because of the severities of reported cases were greatly different and treatments were varied,these patients were divided into 3 levels to get a better understanding of the efficacy.In 6 patients of stage Ⅰ,3 accepted anticoagulation,1 operative treatment,1 endovascular intervention and the left one used more than one methods;the prognosis was good and modified Rankin scale (mRS) score was 0 no matter which kind of therapy was performed.In 11 patients of stage Ⅱ,2 accepted anticoagulation enjoyed mRS scores of 0 and 6,3 operative treatment enjoyed mRS scores of 0,1 and 6,1 endovascular intervention enjoyed mRS scores of 0,and the left 5 used more than one method enjoyed mRS scores of 0,1,1,2 and 2.In 8 patients of stage Ⅲ,1 accepted anticoagulation enjoyed mRS scores of 2,3 operative treatment enjoyed mRS scores of 1,2 and 4,and 4 endovascular intervention enjoyed mRS scores of 0,1,1 and 1.Conclusion It seems that anticoagulation therapy alone may not be effectively enough for those patients that with severe clinical or imaging features;individualized therapy strategies with different types would be more effective.
