Clinical characteristics of Moyamoya disease in the southwest of Shandong Province and its surgical treatment strategies
10.3760/cma.j.issn.1671-8925.2015.04.016
- VernacularTitle:鲁西南地区烟雾病临床特点及其外科治疗策略
- Author:
Song FENG
1
;
Huifu MA
;
Hao ZHANG
;
Lingsheng KONG
;
Feng JIN
Author Information
1. 天津医科大学研究生院
- Keywords:
Cerebral revascularization;
Moyamoya disease;
Surgical treatment
- From:
Chinese Journal of Neuromedicine
2015;14(4):511-515
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical characteristics of patients with Moyamoya disease in the southwest of Shandong province and evaluate the efficacy of cerebral revascularization treatment in it.Methods Clinical data of 96 patients with Moyamoya disease,admitted to our hospital form March 2011 to December 2013,were analyzed retrospectively and compared with those in Japan,South Korea and Inland.Results The clinical characteristics of patients with Moyamoya disease in the southwest of Shandong province were similar with that in Japan,South Korea and Inland,but enjoyed their own particularity:the age distribution showed two peaks (aged 0-10 and aged 31-50) and the sex ratio (female＞male) was similar to those among Japanese and Korean patients,but the age distribution was more concentrated;the incidence of children (12.5％) was significantly lower than that of Japan and South Korea;the main type of Moyamoya disease was the ischemic one (80.2％);the occurrence of transient ischemic attack was higher than that in Japan,South Korea and Inland;the incidences of epilepsy and cerebral infarction were lower than those in Japan,South Korea and Inland;the incidence of cerebral hemorrhage (19.8％) was similar to Japan and Inland,and significantly lower than that in Korea.The clinical symptoms of most Moyamoya disease patients were improved with the treatment of extracranial-intracranial revascularization;and the treatment outcomes showed no significant difference between Chinese,Japanese and Korean.Conclusions The clinical features and pathogenesis mechanism of Moyamoya disease in the southwest of Shandong province may be different form Japan and South Korea.Extracranial-intracranial revascularization is a effective treatment for Moyamoya disease.
