Early diagnosis and surgery in treatment of brain metastases: a clinical analysis of 80 cases
10.3760/cma.j.issn.1671-8925.2015.03.013
- VernacularTitle:早期诊断及手术在脑转移瘤治疗中的作用(附80例临床分析)
- Author:
Zhenghao LIU
1
;
Yuefei DENG
;
Meiguang ZHENG
;
Zhongjun LI
;
Chao LI
Author Information
1. 中山大学孙逸仙纪念医院神经外科
- Keywords:
Brain metastasis;
Early diagnosis;
Microsurgical treatment
- From:
Chinese Journal of Neuromedicine
2015;14(3):278-281
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the experience of early diagnosis and surgical treatment of brain metastases to improve the therapy effect.Methods Retrospective analysis was performed on clinical data of 80 patients with brain metastases,received surgical treatment in our hospital from January 2003 to December 2013.The early diagnosis,treatment and survival of these patients were analyzed.Results Asymptomatic regularly head computerized tomography (CT) or enhanced magnetic resonance imaging (MRI) found 12 patients (15％).Two weeks after surgery,32 patients (40.0％) had totally disappeared neurological disorders,40 (50.0％) had obvious relief,6 (7.5％) were without relieved or even aggravated,and 2 (2.5％) were dead.Eight patients (10.0％) who combined with extracranial metastases died within 6 months of surgery.The one-year survival rate was 60.3％ (47/78),two-year survival rate was 34.6％ (27/78),three-year survival rate was 20.5％ (16/78) and five-year survival rate was 6.4％ (5/78);the median survival was 17 months.In 16 patients of survival more than 3 years,9 were the early-detection asymptomatic patients.Conclusion After resection of primary malignant tumor,the periodical enhanced head CT or MRI are effective measures for early diagnosis of brain metastases; surgical treatment can improve the survival quality and prolong survival time of patients with brain metastases.
