Efficacy comparison of three therapeutic approaches in patients with acute posterior-circulation infarction
10.3760/cma.j.issn.1671-8925.2015.02.012
- VernacularTitle:急性后循环脑梗死三种治疗方法的疗效比较
- Author:
Lili CHEN
1
;
Hongyan ZHAN
;
Sujie WANG
;
Pei LI
;
Jiang LIU
;
Yanhong ZHANG
Author Information
1. 063000,唐山市工人医院神经内科
- Keywords:
Posterior circulation infarction;
Intravenous thrombolysis;
Intral-arterial thrombolysis;
Basilar artery embolectomy;
Stent implantation
- From:
Chinese Journal of Neuromedicine
2015;14(2):162-166
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the therapeutic effects of intravenous thrombolysis,intral-arterial thrombolysis,basilar artery embolectomy combined with stent implantation on patients with posterior-circulation infarction.Methods Fifty-seven patients with acute posterior circulation infarction (onset time within 6 to 72 h),admitted to our hospital from March 2005 to February 2013,were chosen; All subjects were randomly divided into three groups:group A,accepted intravenous thrombolysis (within 6 h of onset),group B,accepted intral-arterial thrombolysis (within 6-24 h of onset),and group C,accepted basilar artery embolectomy and stent implantation (over 24 h of onset).US National Institutes of Health Stroke Scale (NIHSS) was used to observe the clinical symptom improvement,and evaluate the results before and 24 h and 7 d after treatment.Three months after treatment,modified Rankin Scale (mRS) was employed to evaluate the clinical prognosis.Results Significant differences were noted in the treatment efficacy 24 h and 7 d after treatment among the three approaches (P＜0.05):that in group B was obviously higher than that in group A; that in group C was obviously higher than that in group A and B.The mRS scores were significantly different among the three groups (P＜0.05):the clinical outcome improvement in group B was obviously higher than that in group A; that in group C was obviously higher than that in group A and B.Conclusion Different treatments should be adopted based on the specific circumstances of the patients; for those with long time window of thrombolysis,basilar artery embolectomy combined with stent implantation might be more effective in improving the prognosis of the patients.
