Recovery of posterior communicating artery aneurysm-induced oculomotor nerve paresis after endovascular treatment and its related factors analysis
10.3760/cma.j.issn.1671-8925.2015.02.010
- VernacularTitle:后交通动脉瘤性动眼神经麻痹在栓塞术后的恢复情况及相关影响因素分析
- Author:
Shouan WANG
1
;
Chengyan LI
;
Guibin ZHANG
;
Peiyang ZHOU
;
Pu WANG
;
Jun YANG
;
Yuhua FENG
Author Information
1. 441000,襄阳市第一人民医院湖北医药学院附属襄阳医院神经科
- Keywords:
Intracranial aneurysm;
Oculomotor nerve paresis;
Embolization;
Recovery;
Related factor
- From:
Chinese Journal of Neuromedicine
2015;14(2):151-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the evolution of posterior communicating artery (PcomA) aneurysm-induced oculomotor nerve paresis (ONP) and the factors affecting the outcome of ONP after endovascular packing of PcomA.Methods A total of 55 patients with ONP attributable to PcomA,admitted to our hospital from July 2007 to January 2013,were chosen in our study; their clinical data were retrospectively analyzed.The recoveries of ONP were analyzed;univariate analysis and multivariate Logistic regression were used to explore the possible influencing factors of recovery.Results At least one year follow up showed that there was a complete resolution of ONP in 31 patients (56.4％),partial improvement in 19 (34.5％) and no changes in 5 (9.1％).Multivariate Logistic regression analysis indicated that preoperative degrees of paralysis (OR=5.366,95％CI:1.253-22.974,P=0.024),preoperative paralysis time (OR=5.518,95％CI:1.398-21.774,P=0.015) and mecobalamine treatment (OR=6.988,95％CI:1.659-29.431,P=0.008) were significantly associated with the recoveries ofoculomotor nerve function after endovascular treatment.Conclusion Endovascular treatment can promote the recovery of PcomAaneurysm-induced ONP,and preoperative degrees of paralysis,preoperative paralysis time and mecobalamine treatment are factors influencing the complete recovery of ONP.
