Correlation between stenosis of middle cerebral artery and cerebral perfusion
10.3760/cma.j.issn.1671-8925.2015.01.009
- VernacularTitle:大脑中动脉狭窄程度与脑灌注的相关性研究
- Author:
Wenqian SHI
1
;
Jin SHI
;
Fan YANG
;
Huiping SHI
Author Information
1. 北京空军总医院神经内科
- Keywords:
Middle cerebral artery stenosis;
Cerebral perfusion;
Computed tomography perfusion
- From:
Chinese Journal of Neuromedicine
2015;14(1):47-51
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between stenosis of middle cerebral artery (MCA) and cerebral perfusion in patients with unilateral MCA stenosis.Methods Computed tomography perfusion (CTP) was performed in 34 patients with unilateral MCA stenosis,admitted to our hospital trom April 2012 to March 2013.The CTP parameters of mean transit time,cerebral blood flow,cerebral blood volume and time to peak were measured in regions supplied by anterior cerebral artery,MCA and posterior cerebral artery.All patients were divided into severe stenosis group and moderate stenosis group; the correlation between MCA stenosis and cerebral perfusion was analyzed.Results A decreased perfusion was detected in 25 patients (73.5％),and it was more likely found in the severe stenosis group (18/20,90％) than that in the moderate stenosis group (7/14,50％,P=0.017).The degree ofMCA stenosis was positively correlated with the changes of cerebral perfusion (r=0.381,P=0.026).The ratio of patients with transient ischemic attack (TIA) between the normal cerebral perfusion group and decreased cerebral perfusion group had statistical difference (11.11％ vs.72.00％,P=0.004).Conclusion Cerebral perfusion is significantly correlated with the severity of MCA stenosis in unilateral MCA stenosis patients; the proportion of TIA in the low cerebral perfusion patients is higher than that in the normal cerebral perfusion ones.
