Value of ventricular peritoneal shunt in treating patients with intracranial hypertension combined with cryptococcal meningitis
10.3760/cma.j.issn.1671-8925.2014.12.019
- VernacularTitle:脑室腹腔分流术治疗新型隐球菌脑炎合并颅高压的价值探讨
- Author:
Hui WANG
1
;
Cong LING
;
Chuan CHEN
;
Haiyong HE
;
Lun LUO
;
Xinjie NING
;
Xinhua LU
Author Information
1. 中山大学附属第三医院神经外科
- Keywords:
Cryptococcal meningitis;
Intracranial hypertension;
Ventricular peritoneal shunt
- From:
Chinese Journal of Neuromedicine
2014;13(12):1269-1273
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility and safety ofventricular peritoneal shunt (VPS) in treating patients with intracranial hypertension combined with cryptococcal meningitis.Methods Twelve patients with cryptococcal meningitis,admitted to our hospital from January 2012 to January 2014 and underwent VPS for intracranial hypertension,were chosen in our study; the clinical manifestations and cerebrospinal fluid (CSF) results before and after operation,and mannitol dosage before and after operation were compared; follow up for 2-25 months was performed.Results Except 1 patient had no improvement of consciousness,the other 11 patients had disappeared or mitigated headache,disappeared vomiting symptoms,and improved vision and hearing; two patients with disturbance of consciousness got improvement; one patient with eyes abduction got recovery; one patient had abnormal tongue and mouth did not achieve improvement.Different degrees of fever were noted in 10 patients after operation,9 recovered after treatment.The mannitol dosage for all patients were significantly reduced or discontinued.Postoperative cerebrospinal fluid pressure,amount of cryptococcus neoformans in 11 patients were decreased significantly (P＜0.05).Conclusion Early aggressive VPS on cryptococcal meningitis patients with intracranial hypertension is effective and safe.
