Efficacy evaluation of rational application of antibiotics during perioperative period of intracranial operations
10.3760/cma.j.issn.1671-8925.2014.09.017
- VernacularTitle:颅内手术围手术期抗菌药物合理应用效果评价
- Author:
Yan YANG
1
;
Xiaozhu ZHONG
;
Jing ZHANG
;
Xueru YIN
Author Information
1. 南方医科大学珠江医院感染管理科
- Keywords:
Intracranial operation;
Perioperative period;
Rational application;
Antibiotics;
Surgical site infection
- From:
Chinese Journal of Neuromedicine
2014;13(9):944-946
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the rational preventive application of antibiotics during perioperative period of intracranial operations.Methods A prospective study was adopted to investigate the differences of infection rate of surgical site between the group of rational application of antibiotics (406 patients with type Ⅰ incision intracranial operations of neurosurgery in 2011) and the control group (479 patients with type Ⅰ incision intracranial operations ofneurosurgery in 2012).Results The antibiotic treatment period was shortened from (5.16±3.90) days in the control group to (2.77± 1.81) days in group of rational application of antibiotics (t=11.994,P=0.000); while surgical site infection rate was decreased from 14.61％ to 10.10％ (x2=.084,P=0.043).Conclusion Surgical site infection rate in type Ⅰ incision intracranial operations could be reduced and the antibiotic treatment period would be shortened if rational preventive application of antibiotics during the perioperative period could be applied.
