Preoperative functional assessment of epilepsy patients secondary to cerebral hemisphere atrophy by magnetoencephalogram and diffusion tensor imaging
10.3760/cma.j.issn.1671-8925.2014.09.012
- VernacularTitle:脑磁图联合DTI对大脑半球萎缩继发癫痫患者术前功能区评估的价值
- Author:
Tao GUO
1
;
Chuandong LIANG
;
Yujin WU
;
Jilin SUN
;
Jinsheng KANG
Author Information
1. 河北省人民医院功能神经外科
- Keywords:
Cerebral hemisphere atrophy;
Epilepsy;
Functional area;
Magnetoencephalogram;
Diffusion tensor imaging
- From:
Chinese Journal of Neuromedicine
2014;13(9):919-924
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate non-invasive and safe methods for positioning and assessing the functional areas of epilepsy patients secondary to cerebral hemisphere atrophy to reduce postoperative dysfunction.Methods Eight epilepsy patients with cerebral hemisphere atrophy,admitted to our hospital from March 2006 to April 2009,were chosen in our study; magnetoencephalography (MEG) and magnetic resonance diffusion tensor imaging (DTI) were combined to locate the functional areas and assess the functional compensation of these patients.Different surgical methods were adopted according to different results of the patients.All patients were followed up for 12-46 months,averaged 21.6 months.Results MEG could clearly position the cortical sensory,motor,language and visual functional areas of 5 patients,and the other 3 could only be conformed functional areas without clear boundary resulting from their bad cooperation.DTI successfully showed the shape of functional area cortical fibers,which helped the surgery in deciding the extent of resection.Modified hemispherectomy was performed in two patients,multi-lobe resection in five,and temporal lobe resection and hemisphere incision in one; muscles in the contralateral limb of surgery appeared short-term myodynamia weakness and recovery was achieved after rehabilitation exercise.No epileptic seizure was noted in all the patients,enjoying Engle Ⅰ grading.Conclusion Combination of MEG and DTI is a safe,noninvasive method for locating functional areas,could provide security protection for surgical treatment of patients with epilepsy secondary to cerebral hemisphere atrophy.
