Diagnostic value of a simplified psychometric hepatic encephalopathy scale for minimal hepatic encephalopathy
10.3760/cma.j.issn.1671-8925.2014.08.010
- VernacularTitle:简化版肝性脑病心理测试评分量表对轻微型肝性脑病的诊断价值
- Author:
Lei CHEN
1
;
Jiangming ZHAO
;
Yuanbo WU
;
Wenting LI
;
Aimei WU
Author Information
1. 安徽医科大学附属省立医院神经内科
- Keywords:
Simplified psychometric hepatic encephalopathy scale;
Liver cirrhosis;
Minimal hepatic encephalopathy;
Overt hepatic encephalopathy
- From:
Chinese Journal of Neuromedicine
2014;13(8):803-806
- CountryChina
- Language:Chinese
-
Abstract:
Objective The psychometric hepatic encephalopathy scale (PHES),including five psychometric tests,is a standard for the diagnosis of minimal hepatic encephalopathy (MHE) and enjoys predictive value of overt hepatic encephalopathy (OHE).We investigate whether a simplified PHES is as useful as the whole PHES.Methods Seventy consecutive hepatitis B cirrhotic patients without OHE,admitted to our hospital from October 2012 to June 2013,and other 72 healthy volunteers were chosen in our study.PHES was performed in both groups.Expected normal reference value formula were established based on the 5 psychometric tests in healthy controls,and backward logistic regression was performed by eliminating stepwise variables of PHES to get a simplified PHES (SPHES).Then,SPHES was performed on the 70 patients and followed up for a year to detect the prevalence rate of MHE and OHE.Results PHES was easily influenced by age and educational level.In patients with liver cirrhosis,44.29％ patients (31/70) had MHE based on PHES and 41.43％ (9/70) had MHE based on SPHES,without significant differences (P＞0.05).According to the follow-up study,21 patients developed OHE; the number of developing OHE showed no significant difference between MHE patients dignosed by PHES and SPHES (P＞0.05).Conclusion SPHES is as good as PHES in diagnosing MHE and predicting the occurrence of OHE,which consumes less time and is more suitable for clinical screening.
