Correlation analysis of uric albumin/uric creatinine ratio with NEW-TOAST different types in acute cerebral infarction
10.3760/cma.j.issn.1671-8925.2014.08.009
- VernacularTitle:尿白蛋白/尿肌酐比值与急性脑梗死NEW-TOAST分型的相关性分析
- Author:
Jingjuan CHEN
1
;
Chengguo ZHANG
;
Guode LI
;
Guanglun ZENG
;
Piao DU
;
Guohua ZHANG
;
Huahai FENG
Author Information
1. 528000,佛山市第一人民医院神经内科
- Keywords:
Urinary albumin/uric creatinine ratio;
24 hour urinary albumin;
Acute ischemic stroke;
NEW-TOAST typeing
- From:
Chinese Journal of Neuromedicine
2014;13(8):799-802
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the urinary albumin level and urinary albumin/urine creatinine ratio in patients with acute cerebral infarction and explore their relations with NEW-TOAST typing.Methods One hundred and sixty-eight patients with acute cerebral infarction,admitted to our hospital from March 2011 to March 201,were chosen in our study; and other 45 healthy subjects were used as controls; according to NEW-TOAST typing,the patients were divided into different subgroups.Their clinical data were retrospectively analyzed; the 24 hour urinary albumin level and urinary albumin/urine creatinine ratio were detected and their relation was analyzed between patient group and controls,and between patients of different subtypes; besides,the correlation of neurologic impairment (NIHSS) scores with urinary albumin/urine creatinine ratio was analyzed.Results The 24 hour urinary albumin level and urinary albumin/urine creatinine ratio was positively correlated (r=0.301,P=0.001); according to the NEW-TOAST subtypes,patients with large artery atherosclerosis and small artery occlusion had significantly higher level of 24 hour urinary albumin level and urinary albumin/urine creatinine ratio (P＜0.05).NIHSS scores and urinary albumin/creatinine ratio in patient group were positively correlated (r=0.215,P=0.001).Conclusion Acute cerebral infarction and kidney disease are closely correlated;both 24 hour urinary albumin level and urinary albumin/urine creatinine ratio can be the predictor of acute cerebral infarction and influence the prognosis.
