Measurement of ankle-brachial index in patients with stroke subtypes and its clinical significance
10.3760/cma.j.issn.1671-8925.2014.06.017
- VernacularTitle:脑卒中不同亚型踝肱指数测量及其临床意义
- Author:
Guoqiang ZHOU
1
;
Jinsheng ZENG
;
Zongqing HUANG
;
Hongtao LIU
;
Juan ZHANG
Author Information
1. 518033,深圳市福田区人民医院神经内科
- Keywords:
Ankle brachial index;
Stroke;
Subtype;
Atherosclerosis
- From:
Chinese Journal of Neuromedicine
2014;13(6):614-620
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the differences of ankle-brachial index (ABI) in patients with stroke subtypes to explore the clinical significance of ABI in stroke subtypes.Methods Four hundred and seventy-five patients,admitted to our hospital from January 1,2011 to December 30,2012,were classified into the different stroke subtypes by standard of the fourth national cerebrovascular conference:188 patients with atherothrombotic infarction,95 with lacunar infarction,73 with cardiogenic cerebral embolism,85 with intracerebral hemorrhage and 34 with subarachnoid hemorrhage.The normal controls consisted of patients who had no cerebrovascular diseases.ABI was measured in all subjects with Doppler ultrasonic measurement.Statistical analysis was used to analyze the influences of atherosclerosis hazards (including ABI) in stroke,and the difference of ABI in different subtypes of stroke.After adjusting other risk factors,the influence of ABI in stroke subtypes was evaluated alone.Results (1)Multiple factor logistic regression analysis showed that hypertension (odds ratio [OR]=3.963,95％confidence interval[CI]:2.128-6.982,P=0.0001),diabetes mellitus (OR=3.413,95％CI:1.785-4.905,P=0.039),smoking (OR=2.216,95％CI:1.942-6.025,P=0.020),and ABI (OR=2.425,95％CI:1.405-3.512,P=0.012) were significantly correlated with the presence of stroke.(2) Analysis of variance showed that there were significant differences in ABI between the atherothrombotic infarction group and the normal control group (P=0.015),between the lacunar infarction group and the normal control group (P=0.020),between the cardiogenic cerebral embolism group and the normal control group (P=0.037),and between the intracerebral hemorrhage group and the normal control group (P=0.023).After adjusting the risk factors of stroke,disorder multi-classification Logistic regression analysis showed that ABI was negatively correlated to atherothrombotic infarction (OR=2.832,95％CI:1.776-5.273,P=0.011),lacunar infarction (OR=2.527,95％CI:1.548-5.152,P=0.026),cardiogenic cerebral embolism (OR=1.922,95％CI:1.336-3.525,P=0.030),and intracerebral hemorrhage (OR=2.332,95％CI:1.243-4.165,P=0.021).Conclusions ABI is independently and strongly related to the risk of stroke.ABI can serve as screening index of atherothrombotic infarction,lacunar infarction,cardiogenic cerebral embolism,and intracerebral hemorrhage.
