Electroencephalogram slow wave activity of sleep disorders and mild cognitive impairment patients with Parkinson's disease

VernacularTitle:帕金森病合并睡眠障碍和认知功能减退患者脑电图改变
Author: Zhiqiang QI ¹ ; Kezhong ZHANG ; Qiaoying SUN ; Hong ZHOU ; Minyan LU
Author Information

1. 南京医科大学附属江苏盛泽医院神经内科
Keywords: Parkinson's disease; Electroencephalogram; Cognitive function; Sleep disorder
From: Chinese Journal of Neuromedicine 2014;13(6):558-561
CountryChina
Language:Chinese
Abstract: Objective To observe the electroencephalogram (EEG) activity of sleep disorders and mild cognitive impairment (MCI) patients with Parkinson's disease (PD).Methods Forty-nine PD patients,admitted to our hospital from December 2012 to June 2013,were examined by Parkinson's Disease Rating Scale,Hospital Anxiety and Depression Scale,Pittsburgh Sleep Quality Scale (PSQS) and Scale Montreal Cognitive Assessment (MoCA); electroencephalogram and their clinic features were analyzed.Results As compared with the normal sleep and non-MCI patients with PD (61.8％),sleep disorder and MCI patients with PD showed higher incidence of slow wave (65.6％).Logistic regression analysis showed that sleep quality was positively correlated to the incidence of slow wave (OR=4.117,P=0.042).PD patients with slow wave had higher PSQS scores and lower MoCA scores as compared with PD patients without slow wave.Conclusion PD patients with sleep disorder and MCI show high incidence of slow wave.