Changes of cerebral glucose metabolism assessed by positron emission tomography before and after carotid artery stenting in asymptomatic carotid stenosis
10.3760/cma.j.issn.1671-8925.2014.05.018
- VernacularTitle:运用PET评估非症状性颈动脉狭窄支架植入前后脑葡萄糖代谢变化
- Author:
Xuegan LIAN
1
;
Jian WU
;
Shiying SHENG
;
Linfeng ZHU
;
Jingzhong HUANG
;
Meng LIU
;
Hong ZHU
Author Information
1. 苏州大学附属第三医院神经内科
- Keywords:
Carotid artery;
Stenosis;
Glucose;
Standardized uptake value
- From:
Chinese Journal of Neuromedicine
2014;13(5):512-517
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the changes of cerebral glucose metabolism before and after carotid artery stenting (CAS) in patients with asymptomatic carotid stenosis.Methods Eleven patients,admitted to and performed CAS in our hospital from March 2010 to December 2010,were enrolled.The patients received PET-CT examination before and 3 months after CAS (tracking by 18F-FDG).The max standardized uptake value (SUVmax) of each artery supplement area was recorded by region of interest (ROI) method.The metabolism of affected carotid artery area was compared before and after CAS,and the affected carotid area and the unaffected one.Results The SUVmax before CAS in the affected carotid area (4.99±0.96) was significantly lower than that of the unaffected one (5.67±1.27,P＜0.05); follow-up SUVmax in the affected carotid area (5.83 ±1.10) was significantly increased as compared with that before CAS (P＜0.05); follow-up SUVmax in the affected carotid area showed no significant difference as compared with that in the unaffected one after CAS (5.85±1.08,P＞0.05).Conclusion The cerebral glucose metabolism of the affected carotid area decreases significantly,which could be improved after CAS.
