Related factors influencing the progression and prognosis of supratentorial grade Ⅱ gliomas (a report of 65 cases)
10.3760/cma.j.issn.1671-8925.2014.01.012
- VernacularTitle:幕上Ⅱ级胶质瘤发展与预后的多因素分析
- Author:
Xiaoning LIN
1
;
Xinhua TIAN
;
Yanlin HUANG
;
Fenglin ZHANG
Author Information
1. 厦门大学附属中山医院神经外科
- Keywords:
Low grade glioma;
The supratententorial;
Prognosis;
Factor analysis
- From:
Chinese Journal of Neuromedicine
2014;13(1):57-60
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the related factors affecting the progression and early prognosis of patients with supratentorial WHO grade Ⅱ gliomas.Methods Clinical data of 65 patients with supratentorial grade Ⅱ gliomas,treated in our hospital from January 2005 to June 2010,were collected and analyzed.Follow-up was performed for 10-84 months.Univariate analysis was estimated by using Kaplan-Meier method; the differences between groups were analyzed by a log-rank test.The factors (P＜0.05 in univariate analysis) were analyzed by COX proportional hazards regression model in the multivariate analysis.Results Univariate analysis demonstrated that age of onset,initialpresentation,Karnofsky (KPS) scale scores at admission,tumor growth style,tumor enhancement pattern,extent of surgical resection and pathological subtype were associated with progression-free survival time (P＜0.05).Multivariate analysis showed that age,tumor enhancement pattem and extent of resection were significantly associated with progression-free survival time (P＜0.05).Conclusion The progression-free survival time of patients with supratentorial grade Ⅱ gliomas is associated with many factors; age,tumor enhancement pattem and extent of surgical resection were independent risk factors for patients' early prognosis.
