Comparison of incidence of extracranial and intracranial stenosis between patients complicated with pre-diabetes and diabetes
10.3760/cma.j.issn.1671-8925.2013.11.002
- VernacularTitle:糖尿病前期及糖尿病患者合并颅内外血管狭窄的对比研究
- Author:
Tian-Mei XIAO
1
;
Ze-Hong LIN
;
Le-Yu LI
;
Mei-Qi MAI
;
Jing ZENG
;
Ben-Guo WANG
Author Information
1. 广州中医药大学中山附属医院内分泌科
- Keywords:
Pre-diabetes;
Diabetes;
Intracranial artery stenosis;
Extracranial artery stenosis
- From:
Chinese Journal of Neuromedicine
2013;12(11):1087-1090
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the incidence of intracranial and extracranial artery stenosis between patients with different degrees of dysglycemia,and investigate early curative methods of diabetes-related stenosis.Methods One hundred and thirty two consecutive pre-diabetes patients,268 diabetes and 235 healthy controls,collected in our hospital from December 2011 to November 2012,were enrolled; and risk factors,including blood fat,fasting glucose,2-h glucose and fasting insulin,were recruited and analyzed; neck vascular color Doppler and transcranial vascular color Doppler ultrasounds were performed on these patients and compared the incidences of intracranial and extracranial stenoses,single-and multi-branches,and anterior and posterior circulation vascular stenoses among three groups.Results The incidences of intracranial and extracranial stenoses in the control,pre-diabetes and diabetes groups were 5.5％ (13/235),7.6％ (10/132) and 22.4％ (60/268),respectively,with statistical differences (x2=35.738,P=0.000); the incidences of extracranial stenosis,intracranial stenosis,and intracranial and extracranial stenoses in control,pre-diabetes and diabetes groups increased with significant difference (P＜0.05); the incidence of intracranial stenosis of all groups were higher than that of extracranial stenosis.The incidence of multi-branches stenosis in the dysglycemia group were higher than that in the control group with statistical difference (P＜0.05).The incidence of multi-branches stenosis was higher than that of single-branch stenosis in the dysglycemia group.The incidence of anterior circulation stenosis in control,pre-diabetes and diabetes groups increased with significant difference (P＜0.05).Conclusions Dysglycemia related atherosclerotic stenosis maybe stemmed from early stage ofpre-diabetes,and early measurement and administration ofatherosclerotic stenosis should be taken from the early stage.
