Clinical features of children with early-onset benign occipital epilepsy and late-onset children with benign occipital epilepsy and their EEG changes, treatments and prognoses
10.3760/cma.j.issn.1671-8925.2013.07.011
- VernacularTitle:早发性和晚发性儿童良性枕叶癫痫的临床特点、脑电图改变、治疗及预后比较分析
- Author:
Qiao SHAN
1
;
Pei-Dong LI
;
Quan LIU
;
Jian-Heng WU
;
Yue-Hui WU
;
Zhen WANG
;
Jing-Wei XIE
Author Information
1. 郑州大学第五附属医院神经外科
- Keywords:
Early-onset children with benign occipital epilepsy;
Late-onset benign occipital lobe epilepsy of children;
Clinical feature;
Electroencephalogram
- From:
Chinese Journal of Neuromedicine
2013;12(7):696-699
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features of children with early-onset benign occipital epilepsy (EBOS) and children with late-onset benign occipital epilepsy (LOS) and their EEG changes,treatments and prognoses.Methods Sixty children with benign occipital epilepsy,admitted to our hospital from June 2007 to June 2012,were chosen in our study; their clinical data were retrospectively analyzed.According to the recommendations of the 2001 International League against Epilepsy (ILAE),these patients were divided into EBOS group (n=28) and LOS group (n=32); the clinical manifestations,electroencephalogram (EEG) characteristics,medication effectiveness in the two groups of children were compared.Results No significant difference on gender distribution,febrile convulsion histories and family history of epilepsy was noted between the two groups (P＞0.05); however,average ages of onset in the EBOS group were significantly younger than those in the LOS group (P＜ 0.05),and the onset time,seizure frequency,attack mode,seizures associated symptoms and seizure EEG waveforms in the EBOS group were obviously different as compared with those in the LOS group.Single-drug AED treatment could have control effect in 23 of children in the EBOS group and 12 of children in the LOS group; statistical difference was noted between the two groups (P＜0.05).Conclusion The onset time,seizure frequency,attack mode and seizures associated symptoms are obvious different between children with EBOS and LOS,and combined with seizure EEG waveforms,these differences can be used to identify the two.
