Risk predictors of intracranial infection for relapsing meningioma patients underwent reoperation
10.3760/cma.j.issn.1671-8925.2013.05.011
- VernacularTitle:复发脑膜瘤再次手术患者颅内感染的危险因素分析
- Author:
Qing ZHOU
1
;
Ke TANG
;
Jing-An ZHOU
Author Information
1. 解放军第三○九医院神经外科
- Keywords:
Meningioma,neoplasm recurrence;
Postoperative infection;
Risk factor
- From:
Chinese Journal of Neuromedicine
2013;12(5):486-489
- CountryChina
- Language:Chinese
-
Abstract:
Objective To clarify the risk factors contributing to postoperative infection in patients with relapsing meningioma.Methods The clinical characteristics of 187 patients with recurrent meningioma,admitted to our hospital from January 1990 to December 2010,were collected and analyzed retrospectively.The risk factors for postoperative intracranial infection were evaluated by chi-square test.The single factor and multivariate logistic regression analyses were employed to define the independent variables.Results Age,tumor malignancy,diabetes,obesity,organ dysfunction,preoperative long-term bed,preoperative radiotherapy,interval between previous operation and recurrence shorter than or equal to 6 months,preoperative Karnofsky performance status (KPS) scale scores,and postoperative intensive care unit (ICU) therapy were the risk factors for postoperative infections.Multivariate logistic analysis showed that diabetes (OR=21.053,95％CI=5.434-81.567,P=0.000),interval between previous operation and recurrence shorter than or equal to 6 months (OR=34.484,95％CI=1.442-824.793,P=0.029) and KPS scale scores (OR=5.615,95％CI=1.613-19.547,P=0.007) were the independent risk factors.Conclusion Patients with relapsing meningioma,having diabetes,interval between previous operation and recurrence shorter than or equal to 6 months and KPS scores smaller than 70 points have high risk of postoperative infections.
