Efficacy analysis of coagulation disorders of patients with traumatic brain injury after plasma adjuvant therapy
10.3760/cma.j.issn.1671-8925.2013.04.016
- VernacularTitle:血浆辅助治疗脑外伤后凝血功能障碍疗效分析
- Author:
Shi LUO
1
;
Xiao-Bing XU
;
Yan-Wu GUO
;
Zi-Jian LI
;
Hang SU
;
Er-Ning QIU
;
Zhi-Qiang FA
Author Information
1. 528300,佛山市顺德区第一人民医院神经外科
- Keywords:
Traumatic brain injury;
Coagulation disorder;
Frozen plasma
- From:
Chinese Journal of Neuromedicine
2013;12(4):398-400
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the efficacy of plasma adjuvant therapy on coagulation disorders in patients with traumatic brain injury and its relation with the prognosis.Methods Prospective study was performed on patients with traumatic brain injury and coagulation disorders,admitted to our hospitals from January 2010 to June 2012; these patients were divided into conventional treatment group and plasma adjuvant therapy group.Cranial CT was performed and blood coagulation function was checked at admission,and then,coagulation function was re-checked again 3 days after therapy and cranial CT within 3 days.The Glasgow Outcome Scale (GOS) was marked 21 days after treatment.The improvement of coagulation disorders,secondary bleeding and prognosis were compared between the two groups.Results As compared with those in the conventional treatment group,the prothrombin time,partial thromboplastin time,secondary hemorrhage rate in the plasma adjuvant therapy group were significantly reduced (P＜0.05).The differences of D-dimer content and GOS scores between the two groups were not statistically significant (P＞0.05).Conclusion Plasma adjuvant therapy effectively improves the coagulation function,reduces the incidence of intracranial secondary bleeding,but can not obviously improve the prognosis of patients with traumatic brain injury.
