Effects of endovascular embolization treatment on brain damage and recovery of neurological function in patients with posterior communicating artery aneurysm combined with oculomotor nerve palsy
10.3760/cma.j.issn.1671-8925.2013.03.013
- VernacularTitle:血管内介入栓塞治疗对后交通动脉瘤伴动眼神经麻痹患者脑损伤及神经功能恢复的影响
- Author:
Yan-Sheng GAO
1
;
Lai-Jun SONG
Author Information
1. 郑州大学第一附属医院神经外科
- Keywords:
Vascular intervention;
Embolization;
Aneurysm;
Oculomotor nerve palsy;
Brain Injury;
Oculomotor nerve function
- From:
Chinese Journal of Neuromedicine
2013;12(3):275-277
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of endovascular embolization treatment on brain damage and recovery of neurological function in patients with posterior communicating artery aneurysm combined with oculomotor nerve palsy.Methods Eighty-four patients with posterior communicating artery aneurysm combined with oculomotor nerve palsy,admitted to our hospital from January 2007 to January 2011,were chosen in our study; 42 of them used intravascular interventional therapy (group A)and other 42 used microsurgical treatment (group B); the operation time,intraoperative blood loss,time of postoperative recovery respiratory and postoperative extubation time between the groups were compared; and the levels of serum neuron specific enolase (NSE),glucose and lactic acid at the end of the operation,postoperative recovery of the oculomotor nerve palsy and postoperative complications at discharge of the hospital were observed and compared between the two groups.Results As compared with group B,group A had significantly shorter operation time and postoperative extubation time (P＜0.05),and significantly less intraoperative bleeding (P＜0.05); NSE,glucose and lactic acid levels in group A were significantly lower than those in group B at the end of the operation (P＜0.05); the incidence of cerebral vasospasm and cerebral edema in group A were obviously lower than that in group B (P＜0.05).The complete recovery of oculomotor nerve paralysis showed no significant difference between the two groups (P＞0.05).Conclusion As compared with microsurgical treatment,intravascular interventional therapy has good effects (no bleeding,rapid recovery and few complications) in patients with posterior communicating artery aneurysms combined with oculomotor nerve palsy.
