Prevalence, Pathophysiology, Screening and Management of Osteoporosis in Gastric Cancer Patients.
- Author:
Jung Sub LIM
1
;
Jong Inn LEE
Author Information
- Publication Type:Review
- Keywords: Stomach neoplasms; Osteoporosis; Prevalence; Diagnosis; Therapeutics
- MeSH: Aged; Back Pain; Body Mass Index; Chronic Disease; Diphosphonates; Female; Fractures, Spontaneous; Gastrectomy; Humans; Longevity; Male; Malnutrition; Mass Screening; Osteoporosis; Prevalence; Quality of Life; Risk Factors; Stomach Neoplasms; Survival Rate
- From:Journal of Gastric Cancer 2011;11(1):7-15
- CountryRepublic of Korea
- Language:English
- Abstract: Osteoporosis in gastric cancer patients is often overlooked or even neglected despite its high prevalence in these patients. Considering that old age, malnutrition, chronic disease, chemotherapy, decreased body mass index and gastrectomy are independent risk factors for osteoporosis, it is reasonable that the prevalence of osteoporosis in gastric cancer patients would be high. Many surviving patients suffer from back pain and pathological fractures, which are related to osteoporosis. Fractures have obvious associated morbidities, negative impact on quality of life, and impose both direct and indirect costs. In the era of a >55.6% 5-year survival rate of gastric cancer and increased longevity in gastric cancer patients, it is very important to eliminate common sequelae such as osteoporosis. Fortunately, the diagnosis of osteoporosis is well established and many therapeutic agents have been shown to be effective and safe not only in postmenopausal females but also in elderly males. Recently, effective treatments of gastric cancer patients with osteoporosis using bisphosphonates, which are commonly used in postmenopausal woman, were reported.
