Treatment of posterior circulation infarction by Edaravone and Yishen Dingxuan decoction
10.3760/cma.j.issn.1671-8925.2012.08.020
- VernacularTitle:依达拉奉联合益肾定眩汤治疗急性后循环脑梗死32例临床报道
- Author:
Chen-Hao ZHENG
1
;
Zu-Fa LIU
;
Jun WANG
;
Chao-Zhen TONG
;
Yi-Jie LI
Author Information
1. 中国中医科学院望京医院
- Keywords:
Edaravone;
Yishen Dingxuan decoction;
Infarction;
Posterior circulation
- From:
Chinese Journal of Neuromedicine
2012;11(8):835-837
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the treatment efficacy of Edaravone and Yishen Dingxuan decoction on patients with posterior circulation infarction. Methods Sixty-three patients with posterior circulation infarction,admitted to our hospital from January 2010 to June 2011,were randomly divided into treatment group (n=32) and control group (n=31); treatment group was treated by Edaravone (intravenous infusion) and Yishen Dingxuan decoction (per os),and Yishen Dingxuan decoction was composed of Tianma,Gouteng,Chuanxiong,Jixueteng,Baizhu,Zexie,Banxia,Shanyurou,Huangqi,Gouqi and Heshouwu.Control group was treated by edaravone (intravenous infusion) and Shuxuetong.National Institutes of Health Stroke Scale (NIHSS) was performed before and 14 d after the treatment; the decrement of the scores (the symptom improvement degree) was used as index to evaluate the efficacy.Results The NIHSS scores in the treatment group (4.564 ±1.350) were significantly different as compared with those in the control group ([7.976+ 1.830],t=6.587,P=0.021 ).Rank-sum test indicated that grade distribution of the efficacy between the 2 groups was significantly different (Z=-2.338,P=0.019),and mean rank test further proved that the treatment efficacy in treatment group (26.89) was better than that in the control group (37.27) Conclusion The treatment efficacy of Edaravone and Yishen Dingxuan decoction in patients with posterior circulation infarction is good.
