Image changes of head proton magnetic resonance spectroscopy in children with epilepsy

VernacularTitle:癫痫患儿头颅氢质子磁共振波谱改变的研究
Author: Qiong-Xiang ZHAI ¹ ; Chun WANG ; Qian CHEN ; Yu-Xiong GUO ; Yu-Xi ZHANG ; Zhi-Hong CHEN ; Biao HUANG
Author Information

1. 广东省人民医院
Keywords: Epilepsy; Magnetic resonance spectroscopy; Functional imaging
From: Chinese Journal of Neuromedicine 2012;11(8):804-806
CountryChina
Language:Chinese
Abstract: Objective To investigate the image changes of proton magnetic resonance spectroscopy (1H-MRS) in children with epilepsy and their clinical significance. Methods Sixty-four patients with epilepsy,admitted to our hospital from March 2008 to March 2011,and 10 healthy children as control group were chosen in our study; the patients were divided into MR normal group and MR abnormal group according to the results of MR imaging. All of them received 1H-MRS examination on the hippocampal area.The ratio of NAA/Cho+Cr was compared between each 2 groups. Results No significant differences on the ratio of NAA/Cho+Cr were noted between the fight and left sides in all the groups (P＞0.05).The ratio of NAA/Cho+Cr was significantly different:MR normal group and control group enjoyed obvious difference as compared with MR abnormal group (P＜0.05); however,MR normal group and MR abnormal group existed no statistically significant differences (P＞0.05). Conclusion 1H-MRS is more sensitivity than MRI in children with epilepsy,therefore,1H-MRS can find the lesions earlier than MR imaging.