Clinical efficacy of embolization in treating cerebral arteriovenous malformations using a new liquid embolic agent
10.3760/cma.j.issn.1671-8925.2012.07.022
- VernacularTitle:福爱乐医用胶栓塞治疗颅内动静脉畸形
- Author:
Fan WANG
1
;
Xian-Hong XIANG
;
Hua YANG
;
Jian LIU
;
Liang-Zhao CHU
;
Jian-Mei SUI
;
Ming YANG
;
Gang PENG
Author Information
1. 贵阳医学院附属医院
- Keywords:
FuAiLe medical adhesive;
Embolization;
Central nervous system;
Arteriovenous malformation
- From:
Chinese Journal of Neuromedicine
2012;(7):734-736
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To study the clinical efficacy of embolization in treating cerebral arteriovenous malformations(AVMs) using a new liquid embolic agent,FuAiLe medical adhesive (FAL,main ingredients:α-octyl cyanoacrylate and α-butyl cyanoacrylate).[Methods]Femoral artery was catheterized under local anesthesia,and then superselective catheterization to intracranial lesions were obtained using marathon 1.3F microcatheter.Fifteen cerebral AVMs were embolized by FAL.The diameter of AVMs was larger than 6 cm in 4 cases,3-6 cm in 7 cases and smaller than 3 cm in 4 cases.Single blood supply was observed in 3 cases,2 blood supplies in 5 cases and 3 blood supplies in 7 cases.Surgical ablation was applied after embolization in 3 cases,and gamma knife treatment was applied after embolization in 2 cases,[Results] A total of 26-time embolization was obtained in 15 patients;more than 80％ embolization was achieved in 8 cases,including 5 with complete embolization;and 50％-80％ embolization was achieved in 5 cases;less than 50％ embolization was achieved in only 2 cases.No serious complication associated with embolization was noted in all patients.[Conclusion] It is safe and effective for FAL to treat cerebral AVMs and FAL may be an ideal embolic agent.
