Efficacy and cost analysis of microsurgical clipping and vascular embolization in treatment of patients with cerebral aneurysms
10.3760/cma.j.issn.1671-8925.2012.07.016
- VernacularTitle:显微手术夹闭与血管栓塞术治疗脑动脉瘤的疗效与成本分析
- Author:
Chun-Xiao MA
1
;
Xing-Yao BU
;
Wei ZHOU
;
Ya-Zhou XING
;
Jian-Guo ZHANG
;
Suo-Cheng GUO
;
Zhao-Yue YAN
;
Xiang-Yu XUE
;
Wei-Xing BAI
Author Information
1. 河南省人民医院
- Keywords:
Cerebral aneurysm;
Microsurgical clipping;
Vascular embolization;
Efficacy;
Cost analysis
- From:
Chinese Journal of Neuromedicine
2012;(7):709-712
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To investigate the efficacy and cost analysis ofmicrosurgical clipping and vascular embolization in the treatment of patients with cerebral aneurysms.[Methods]Two hundred and fitly-one patients with cerebral ameurysms,admitted to our hospital from January 2007 to December 2010,were collected in our study;170 patients (174 aneurysms) received microsurgical surgical clipping (clipping group) and other 181 patients (185 aneurysms) were performed vascular embolization (embolization group).Duration of hospitalization,vascular occlusion rate,intraoperative rupture rate,hospital mortality and happening of complications were compared between the 2 groups;and the efficacy were evaluated by modified Rankin scale (mRS) and cost analysis of the 2 treatments were compared 3 months after the surgeries.[Results] The length of hospital stays and cerebral aneurysm rupture rate in patients of the embolization group were significantly shorter/lower than those in the clipping group (P＜ 0.05);the scores of mRS showed no significant differences between the 2 groups (P＞0.05).The cost and sensitivity analysis indicated that the ratio of average cost/good prognosis rate in the clipping group was smaller as compared with that in the embolization group.[Conclusion] The efficacies of microsurgical clipping and embolization in the treatment of cerebral aneurysms are considerable,and both of them have their advantages and disadvantages respectively;however,the microsurgical clipping is cost-effective and economical.
