Stereotactic lesioning of the amygadala and hippocampus in patients with epilepsy of the mesial temporal lobe
10.3760/cma.j.issn.1671-8925.2012.06.002
- VernacularTitle:立体定向杏仁核海马毁损术治疗颞叶内侧型癫痫的临床研究
- Author:
Shu-Hang WEI
1
;
Song-Tao QI
;
Kai-Jun YANG
Author Information
1. 广州中医药大学附属佛山市中医院
- Keywords:
Stereotactic surgery;
Epilepsy;
Ablation of amygadala and hippocampus
- From:
Chinese Journal of Neuromedicine
2012;11(6):545-548
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of stereotactic lesioning of the amygadala and hippocampus for treatment of epilepsy in the mesial temporal lobe, and explore the accuracy of lateralization and localization of interictal epileptic discharge recorded by depth electrode. Methods Twenty-one patients with intractable epilepsy of the temporal lobe,admitted to our hospital from July 1998 to October 2003 and underwent stereotactic lesioning of the amygadala and hippocampus,were chosen in our study. The frequentcy of Interictal epileptic discharge recorded by depth electrode and occurred preoperatively and postoperatively were compared Results Follow-up was performed in 21patients:6 with Engel Ⅰ,2 with Engel Ⅱ,5 with Engel Ⅲ,3 with Engel Ⅳ and 5 with Engel V.Thirteen patients enjoyed good effect and ineffective result was noted in 8,with an effective rate reaching 62％.No consistent changes of interictal epileptic discharge recorded by depth electrode occurred preoperatively.Conclusion Stereotactic lesioning of the amygadala and hippocampus is safe and effective in treating patients with epilepsy in the mesial temporal lobe.The interictal epileptic discharge can supply useful lateralizing information,but has little localizing value.
