Diagnosis and treatment of ectopic pituitary adenoma: a report of 3 cases and literature review
10.3760/cma.j.issn.1671-8925.2012.05.019
- VernacularTitle:异位垂体腺瘤的诊断与治疗(附三例报告并文献复习)
- Author:
Lun-Xian YANG
1
;
Yuan-Jie ZOU
;
Chao-Yong XIAO
;
Zhu-Hai L(U)
Author Information
1. 南京医科大学附属脑科医院
- Keywords:
Pituitary adenoma;
Ectopic;
Diagnosis;
Treatment
- From:
Chinese Journal of Neuromedicine
2012;11(5):516-518
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the conception,mechanism,clinical manifestations,diagnosis,treatment and prognosis of ectopic pituitary adenoma. Methods The clinical data of 3 patients with ectopic pituitary adenoma, admitted to our hospital from October 2010 to March 2011, were retrospectively analyzed and discussed by reviewing the relevant literature. Results Clinical manifestations ofectopic pituitary adenoma were as follows:2 had headache,1 had sexual dysfunction and blurred vision, and 1 had acromegalia combined with psychiatric symptom. Endocrinological examination showed that 1 had obviously increased growth hormone (GH) and 1 increased prolactin (PRL).MRI scan indicated that 2 were located in sphenoid sinus and I was located in the sphenoid sinus and clivus.Contrast-enhanced MRI showed enhanced lesions.Total removal was achieved in 2 patients through the trans-sphenoidal approach; partial removal was achieved in the patient with sphenoid sinus and clivus.Pathology examination demonstrated as pituitary adenomas. Conclusion The patients with ectopic pituitary adenoma have neurological dysfunction or/and endocrinological dysfunction; CT and MRI play valuable role in their diagnosis; radical resection of tumor can achieve satisfactory clinical outcomes.
