Influence of HBO therapy on level of ACA-IgG and thrombomodulin among parents with ischemic encephalopathy
10.3760/cma.j.issn.1671-8925.2012.01.023
- VernacularTitle:高压氧治疗对缺血性卒中患者ACA-IgG及TM水平的影响
- Author:
Zhe-Cong LIN
1
;
Cong GAO
;
Ting-Ting ZHAN
;
Mei-Rong LIN
;
Wei LI
Author Information
1. 广州医学院附属第二医院
- Keywords:
Ischemic encephalopathy;
IgG antipholipid antibodies;
Thrombomodulin;
Hyperbaric oxygen
- From:
Chinese Journal of Neuromedicine
2012;11(1):91-94
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of HBO on the change of levels of ACA and thrombomodulin among parents with ischemic encephalopathy. Methods Patients were divided into three groups: group A (patients with atherosclerosis and thrombosis),group B (patients with cardiogenic embolism) and group C (patients with small artery lesion). All patients were treated with HBO and regular drugs. And then sss scores were recorded and levels of ACA-IgG and thrombomodulin were detected by ELISA before and after therapy of HBO. Results The index of ACA-IgG and lelvel of TM in A,B and C group were higher than those in control group,there are differences among them(P＜0.05),and the level of them were higher in B group than in A and C group.There were significant differences in SSS score for brain function using different therapies in A、B and C group (P＜0.05), but there are no differences among them(P＞0.05).There were differences in the index of ACA-IgG and thrombomodulin using different therapies in A,B and C group(P＜0.05),however,there were no differences among them (P＞0.05). Conclusion HBO can alleviate clinical symptoms and improve recovery of neuron by decreasing the level of ACA-IgG and thrombomodulin in blood,but the effect is not significantly different for ischemic encephalopathy caused by different factors.
