Seropositive Myasthenia Gravis Associated with Small-Cell Lung Carcinoma.
- Author:
Masayuki OHIRA
1
;
Dushin JEONG
;
Shin J OH
Author Information
- Publication Type:Case Report
- Keywords: acetylcholine receptor antibody; myasthenia gravis; small cell lung cancer
- MeSH: Acetylcholine; Aged; Electromyography; Humans; Lambert-Eaton Myasthenic Syndrome; Lung; Myasthenia Gravis; Paraneoplastic Syndromes; Respiratory Insufficiency; Small Cell Lung Carcinoma
- From:Journal of Clinical Neurology 2011;7(1):43-46
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: Lambert-Eaton myasthenic syndrome is well known to be a classical paraneoplastic syndrome of small cell lung carcinoma (SCLC). Three cases of seronegative myasthenia gravis (MG) and SCLC were previously reported. CASE REPORT: A 65-year-old man developed a severe progressive respiratory failure with clinical features of MG. Tests showed a decremental response in the repetitive nerve stimulation test, abnormal single-fiber electromyography, and positive acetylcholine receptor antibody. SCLC was confirmed by the lung biopsy. CONCLUSIONS: This case represents the first case of seropositive MG and SCLC.
