Prognosis of patients with post-traumatic epilepsy at early time after traumatic diffuse axonal injury

VernacularTitle:弥漫性轴突损伤后早期并发癫痫患者的预后研究
Author: Jin LI ¹ ; Ling-Hui LIU ; Zhi-Sheng CHEN
Author Information

1. 暨南大学附属第一医院
Keywords: Diffuse axoual injury; Post-traumatic epilepsy; Prognosis
From: Chinese Journal of Neuromedicine 2011;10(12):1207-1210
CountryChina
Language:Chinese
Abstract: Objective To explore the prognosis of patients with post-traumatic epilepsy at early time after traumatic diffuse axonal injury(DAI).Methods One hundred and eighty-seven patients with DAI,admitted to our hospital from January 2000 to June 2011,were chosen; 26 DAI patients were complicated with post-traumatic epilepsy(PTE)at early time(within 2 weeks of injury),and the other 78 DAI patients without PTE were chosen as control group.Prognosis and activity of daily living(ADL)of these patients were evaluated with Glasgow Outcome Scale (GOS) and Barthel index.Results Significant differences on prognosis and ADL were noted between patients with and without PTE(P＜0.05); the prognosis of DAI patients attacked by PTE at early time was obviously worse than that of the ones who were not.DAI patients with PTE had low ADL than those patients without PTE.Conclusion Attacking by PTE at early time can obviously influence the prognosis of patients with DAI; especially for severe patients,the prognosis is obvious bad,and the mortality and disability rate increase significantly.