Impulsiveness and risk-taking decision-making in heroin addicts
10.3760/cma.j.issn.1671-8925.2011.11.023
- VernacularTitle:海洛因成瘾者冲动行为与风险决策的研究
- Author:
Bin LIN
1
;
Ruo-bing N QIA
;
Xian-Ming FU
;
Xue-Bing JI
;
Xiang-Pin WEI
;
Wen-Fu HU
;
Tao YI
;
Chang-Xin WANG
;
Chaoshi NIU
;
Ye-Han WANG
Author Information
1. 安徽医科大学附属省立医院
- Keywords:
Heroin addiction;
Impulsiveness;
Risk-taking decision-making;
Prefrontal cortex
- From:
Chinese Journal of Neuromedicine
2011;10(11):1168-1171
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the reaction patterns of impulsiveness and risk-taking decision-making in heroin addicts and their significance.Methods Seventeen heroin addicts(HA group)admitted to Detoxification and Rehabilitation Center of Anhui Province from July 2010 to December 2010 and 18 healthy controls(HC group)recruited at the same period were performed Iowa gambling task(IGT)and Risky-Gains task(RGT),respectively; the different capacities of impulsiveness control and risk-taking decision-making between HA group and HC group were compared.Results As for IGT,decision-making course affected the net scores remarkably in HC group,whereas contrary result was observed in HA group(P＜0.05); no statistical difference between the numbers of low-frequency punishment cards and high-frequency punishment cards which subjects selected was noted in HA group,while statistical difference was observed in HC group(P＜0.05).Furthermore,the difference between the number of low-frequency punishment cards and high-frequency punishment cards in HC group was higher than that in HA group(P＜0.05).In RGT,as compared with risky response rate before punishment,risky response rate after punishment declined notably in HC group,while no significant changes were seen in HA group; risky response rate after reward and after punishment in HA group were significantly higher than those in HC group(P＜0.05).Conclusion As evidence of chronic heroin addicts' behavior,heroin addict exsits impulsiveness and deficit in risk-taking decision-making,which may be one of the causes of generation and maintenance of heroin addiction.
