Carotid angioplasty and stenting and medicine in treating patients with symptomatic carotid artery stenosis
10.3760/cma.j.issn.1671-8925.2011.10.016
- VernacularTitle:颈动脉支架植入术及药物治疗症状性颈动脉狭窄的临床研究
- Author:
Xiu-E WEI
1
;
Zhong-Hai TAO
;
Liang-Qun RONG
;
Chun-Feng LIU
Author Information
1. 苏州大学附属第二医院
- Keywords:
Carotid artery stenosis;
Stent;
Medical therapy
- From:
Chinese Journal of Neuromedicine
2011;10(10):1034-1037
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the safety,efficacy and complications of carotid angioplasty and stenting (CAS) in patients with symptomatic carotid artery stenosis,and compare it with medical therapy.Methods Fifty-two patients with symptomatic carotid artery stenosis,admitted to our hospital from May 2005 to May 2010,were performed CAS,and the other 63 patients with symptomatic carotid artery stenosis admitted to our hospital at the same period were adopted medical therapy.Patients of both groups were followed-up for 3,6 and 12 months,and 1 y; the incidence of ischemic stroke or transient ischemic attack (TIA) were compared and the NIHSS scores were noted between the 2 groups.Results The operation was terminated in 1 patient because of poor operation path; carotid sinus reflex occurred in 9 during intraoperative or postoperative periods; vascular spasm occurred in 2; hyperperfusion syndrome occurred in 4 during intraoperative period,but no serious consequences were noted in patients performed CAS after being given timely and effective treatment.Stroke recurred after 3 months in the patient whose operation was failed; no stroke or TIA recurred in the other patients during the 1-y-follow-up period; and 1 recurred after 1 y in patients received CAS.There are 11,9,7 and 12 patients had stroke or TIA attack during the 3,6 and 12 months,and 1 y follow-up period,respectively,in patients given medical therapy.As compared with those in the patients given medical therapy,the NIHSS scores during the 3,6 and 12 months,and 1 y follow-up period in patients received CAS were significantly lower (P＜0.05).Conclusion The CAS is a safe and feasible method in patients with symptomatic carotid artery stenosis;as compared with medical therapy,it can prevent recurrence of stroke more effectively.
