Dynamic observation of cerebral vasoreactivity after carotid angioplasty and stenting
10.3760/cma.j.issn.1671-8925.2011.01.016
- VernacularTitle:颈动脉支架置入术后颅内血管反应性动态观察
- Author:
Hui-Min ZHU
1
;
Deng-Yue ZHAI
;
Qin YIN
;
Zhen HONG
;
Zhi-Ming ZHOU
;
Ge-Lin XU
;
Xin-Feng LIU
Author Information
1. 南京大学医学院临床学院(南京军区南京总医院)
- Keywords:
Carotid artery stenosis;
Carotid angioplasty and stenting;
Breath-holding index;
Follow-up
- From:
Chinese Journal of Neuromedicine
2011;10(1):66-69
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes and influencing factors of cerebral vasoreactivity (CVR) in patients after carotid angioplasty and stenting (CAS). Methods Thirty-seven patients performed CAS, admitted to our hospital from July 2008 to September 2009, were finished the follow-up and chosen in our study; the breath-holding index (BHI) of the bilateral middle cerebral artery was measured using transcranial Doppler combined with breath holding test before thc operation, and 1 d and 3-10 months after the operation. Repeated measures design analysis of variance was employed to detect the BHI changes before and after the stenting; multiple regression was employed to analyze the influencing factors of BHI. Results BHI values after stenting were significantly higher than those before stenting on the stenotic side (P＜0.05). The follow-up BHI values were negatively correlated with those of tandem stenoses (β=-0.016, P=0.002) and positively correlated with the postoperative BHI values (β=1.030, P=0.000). Conclusion CAS can immediately improve CVR on the ipsilateral side and make it close to normalization gradually. Tandem stenoses are the independent risk factors of CVR.
