Therapeutic efficacy of auxiliary early-adoption of Xinnao shutong capsules in senile patients with acute ischemic stroke
10.3760/cma.j.issn.1671-8925.2010.12.024
- VernacularTitle:老年急性缺血性脑卒中患者早期辅助服用心脑舒通胶囊的临床疗效观察
- Author:
Ye MA
1
;
Jian-Fang MA
;
Sai-Qing XIE
Author Information
1. 福州军区福州总医院
- Keywords:
Acute ischemic stroke;
Xinnao shutong capsules;
Neurological function;
Clinical efficacy
- From:
Chinese Journal of Neuromedicine
2010;09(12):1274-1276
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the efficacy of auxiliary early-adoption of Xinnao shutong capsules on anti-cerebral ischemia and neurological protection in senile patients with acute ischemic stroke. Methods Eighty senile patients with acute ischemic stroke were equally randomized into control group and treatment group. Conventional treatment was given to the control group; besides the conventional treatment, the Xinnao shutong capsules at a dosage of 3 pills and three- times daily for 30 d was given to the treatment group. The clinical efficacy and European stroke scale (ESS) scores were recorded and evaluated. Results The ESS scores in the treatment and control groups before the treatment were (56.24±10.48) and (57.73±9.85), respectively. The ESS scores in the treatment group on the 15th and 30th d of treatment (65.41±11.82, 72.52±13.21) was significantly improved as compared with those in the control group (59.52±10.13, 62.48±12.73) (P<0.05). Significant differences on the clinical efficacy were noted between the 2 groups (Z=-2.813, P=0.005). Conclusion Xinnao shutong capsules have the effect of anti-cerebral ischemia and decreasing the neurological deficits in patients with acute ischemic stroke.