Effect of prophylactic administration of atropine before carotid angioplasty and stenting on cardiovascular system
10.3760/cma.j.issn.1671-8925.2010.12.017
- VernacularTitle:颈动脉支架置入术前预防性应用阿托品对心血管系统的影响
- Author:
Min LIN
1
;
Xue-Gan LIAN
;
Jin FAN
;
Deng-Yue ZHAI
;
Guang-Hui CHEN
Author Information
1. 第二军医大学南京临床医学院(南京军区南京总医院)
- Keywords:
Carotid artery;
Stenting;
Hypotension;
Bradycardia;
Atropine;
Complication
- From:
Chinese Journal of Neuromedicine
2010;09(12):1250-1254
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of prophylactic administration of atropine before carotid angioplasty and stenting (CAS) on the happening of intraoperative and postoperative hypotension,bradycardia or cardiovascular complications. Methods Seventy-seven patients with carotid atherosclerosis, admitted to our hospital from November 2008 to May 2010 and performed CAS, were chosen in the study. Prophylactic administration of atropine before CAS was performed on 42 patients and the other 35 without atropine administration were adopted as control group. The clinical data of these patients were analyzed and the high risk factors of cardiovascular events (hypotension or bradycardia) at the perioperative period were observed. The incidence of cardiovascular complications at the perioperative period was also recorded and compared. Results No significant differences on the clinical data, high risk factors of cardiovascular events and morphological characteristics of the vessels were noted between the 2 groups (P＞0.05). The operation procedures were almost the same between the 2 groups. As compared with the control group, the atropine treatment group enjoyed significantly lower incidences of intraoperative or perioperative bradycardia and cardiovascular complications at the perioperative period (P＜0.05). Conclusion The prophylactic administration of atropine before CAS decreases the incidence ofbradycardia and cardiovascular complications during and after CAS.
