Multi-target derogation operation of senile dementia in patients with mental disorder: an efficacy analysis
10.3760/cma.j.issn.1671-8925.2010.09.021
- VernacularTitle:多靶点毁损治疗老年期痴呆合并精神障碍患者的疗效分析
- Author:
Qin-Fen WU
1
;
Wen-De ZHANG
;
Zhi-Hao ZOU
;
Jie YIN
;
Xi ZHENG
;
Dong-Dong WANG
;
Wei-Feng GENG
Author Information
1. 解放军第474医院
- Keywords:
Senile dementia;
Mental disorder;
Stereotactic techniques;
Target
- From:
Chinese Journal of Neuromedicine
2010;09(9):948-950
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical effects of stereotactic radiofrequency multitarget lesion on the treatment of senile dementia in patients with mental disorder. Methods Under the CT localization, 18 patients with mental retardation were treated by stereotactic surgery of multi-target lesion.Their therapeutic effects were evaluated by Scale and National Psychosurgery Cooperation Request on Modern Psychosurgery Operation Cure (protocol) in 1990. Results Postoperative follow-up was performed for 12-36 months; 9 patients progressed remarkably; 6 got improvement and only 3 showed no changes; the total effective rate was 83.3%. The scores of brief psychiatric rating scale, social disability screening schedule and scale for assessment of positive symptoms after the treatment were significantly lower than those before the treatment (P＜0.05). Mini-mental state examination showed no changes on the intelligence before and after the treatment (P＞0.05). Conclusion The stereotactic surgery of multi-targets lesion is an effective method in treating senile dementia in patients with mental disorder,with few complications and little influences on the intelligence.
