Hyperbaric oxygen and right median nerve electrical stimulation on coma arousal therapy in patients with severe traumatic brain injury
10.3760/cma.j.issn.1671-8925.2010.08.018
- VernacularTitle:高压氧及右正中神经电刺激对重型颅脑外伤患者的术后催醒作用
- Author:
Min HE
1
;
Zhen-Jia LU
;
Jin-Shan LI
;
Xin-Ming YANG
;
Jing GUO
Author Information
1. 上海安达医院
- Keywords:
Traumatic brain injury;
Hyperbaric oxygen;
Electrical stimulation;
Right median nerve
- From:
Chinese Journal of Neuromedicine
2010;09(8):823-826,836
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of hyperbaric oxygen (HBO) and right median nerve electrical stimulation (RMNS) on the coma arousal therapy in patients with severe traumatic brain injury. Methods Eighty-three patients with severe traumatic brain injury on the recovery phase were randomly divided into control group (n=41) and treatment group (n=42). The patients in the control group were given such routine therapies as reducing the intracranial pressure and giving nutrition to the nerves and conventional rehabilitation nursing. The patients in the treatment group also treated with HBO and RMNS. Glasgow coma scale (GCS), Glasgow outcome scale (GOS), activities of daily living (ADL)scale, European stroke scale (ESS) and Kamofsky performance scale (KPS) were performed on these patients before, 1 and 3 after the treatment. The cerebral blood flow (CBF) and the electrical activity were detected by TCD and brain electrical activity mapping (BEAM). Results As compared with thecontrol group, the treatment group got significant improvement on each scale in the 1st and 3rd month oftreatment (P＜0.05). CBF in the treatment group was obviously increased, while that in only 17 patients in the control group was increased. BEAM showed that the diffused inactive echoes were significantly decreased in the treatment group as compared with those in the control group. Conclusion HBO andRMNS can promote brain tissue rehabilitation and accelerate recovery of brain function in patients with severe traumatic brain injury, thereby contributing to the improvement of the level of awareness.
