Value of Montreal cognitive assessment in identifying patients with mild vascular cognitive impairment after first stroke
10.3760/cma.j.issn.1671-8925.2010.05.016
- VernacularTitle:蒙特利尔认知评估量表识别首次卒中后轻度血管性认知障碍的作用
- Author:
Yan-Ping WANG
1
;
Gui-Lan XU
;
Shao-Qing YANG
;
Xiang-Min LIU
;
Xiao-Ying DENG
Author Information
1. 广州医学院附属第二医院
- Keywords:
Montreal cognitive assessment;
Mini-mental state examination;
Mild vascular cognitive impairment
- From:
Chinese Journal of Neuromedicine
2010;9(5):503-507
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the value of Montreal cognitive assessment (MoCA) in identifying the patients with mild vascular cognitive impairment after first stroke (mVCI-FS), and compare it's results with those of mini-mental state examination (MMSE). Methods MoCA and MMSE were performed on 60 patients with mVCI-FS and 25 with non mild vascular cognitive impairment after first stroke (nVCI-FS) by neurologists 12±1 w after the onset. Results Total mean scores of MoCA was 19.78±4.57 and that of MMSE was 25.48±3.14 with the partial correlation reaching r=0.779 and P=0.000. Significant differences in each sub-items of MoCA were found between mVCI-FS group and nVCI-FS group, except calculation and verbal fluency (P<0.05); no significant difference in immediate memory, calculation, naming and reading comprehension of MMSE was noted between the 2 groups (P>0.05). The initial optimal cut-off-point of MoCA was 21 in identifying mVCI-FS from nVCI-FS according to the ROC curve analyses as well as the largest youden's index. With the cut-off-point of 21,MoCA Can provided a sensitivity of 84.6% and a specificity of 76.0%,respectively,for screening mVCI-FS, which was much better than MMSE (sensitivity 59.6% and specificity 57.7%)Conclusions The initial optimal cut-off-point of MoCA is 21 in identifying mVCI-FS from nVCI-FS.MoCA, having high sensitivity and specificity in screening mVCI-FS, is a valid screening scale in screening mVCI-FS; however, MMSE, showing poor sensitivity in screening mVCI-FS, cannot be a reliable instrument in screening mVCI-FS.
