Percutaneous endoscopic gastrostomy in nutritional supporting and pulmonary infection preventing of coma patients with severe brain injury
10.3760/cma.j.issn.1671-8925.2010.05.014
- VernacularTitle:经皮微创胃造瘘后营养支持治疗重型颅脑损伤昏迷患者疗效观察
- Author:
Ping-Hua QIU
1
;
Shao-Ming CAI
;
Xi-Fen YAO
;
Yu-Sheng WANG
;
Peng-Fei WANG
Author Information
1. 广东省揭阳市人民医院
- Keywords:
Gastrostomy;
Pulmonary infection;
Severe brain injury
- From:
Chinese Journal of Neuromedicine
2010;9(5):496-499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of percutaneous endoscopic gastrostomy on coma patients with severe brain injury in preventing the pulmonary infection and supporting the nutritional therapy. Methods Forty coma patients with severe brain injury and 2 dysphgia patients with brain stem infarction, admitted to our hospital from January 2006 to December 2009 were chosen as experimental group and given nutritional therapy after percutaneous endoscopic gastrostomy. The other 42 coma patients with severe brain injury admitted to our hospital at the same period were chosen as control group and given nasal-feeding nutrition. The degree of lung infection and the contents of serum total protein, serum albumin and hemoglobin 1 w before, and 1 and 2 w after the surgery in the 2 groups were detected. Results All of the patients (40 in coma and 2 not being able to eat) benefited from percutaneous endoscopic gastrostomy: the pulmonary infection caused by esophageal back flow was prevented; the infection rate of G+ pathogenic bacteria and the G-pathogenic bacteria in the experimental group was 0significantly decreased as compared with that in the control group (P<0.05). No significant differences of the contents of serum total protein, serum albumin and hemoglobin at each time points between the 2 groups were noted (P>0.05). Conclusion Nutritional therapy after adopting the percutaneous endoscopic gastrostomy, preventing pulmonary infection caused by esophageal back flow, is a safe method and worth to be generalized.