Effect of denervation of masseter muscle on the development of mandible
10.3760/cma.j.issn.1671-8925.2010.03.011
- VernacularTitle:咬肌去神经对下颌骨发育影响的实验研究
- Author:
Jin-Jun HUANG
1
;
Lei SHAN
;
Da-Lie LIU
;
Jin-Huang WANG
Author Information
1. 南方医科大学珠江医院
- Keywords:
Mandible;
Denervation;
Growth and development;
Masseter muscle
- From:
Chinese Journal of Neuromedicine
2010;9(3):262-265
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of denervation of masseter muscle on the development of mandible.Methods Twenty-four 28-day-old Wistar rats were randomly divided into operative(n=9),sham-operative(n=9)and control(n=6)groups.The main trunk and initial branches of the masseter nerve on the right side were resected in the operative group.The nerve was exposed,but not resected in the sham-oporative group.The control group was only anaesthetised.CT scan and 3D reconstruction were performed when the rats were 75 d old.Seven cephaiometric points were selected and digitized and selected 7 linear distances were measured.The rots were killed with an overdose of 10% chloral hydrate after the CT scan.Masseter muscles on each side were obtained and weighted immediately.Results The mass of the mandible of the operative side was significantly lighter than that of the non-operative side in the operative group(P<0.05).No significant variances on length of the mandible Ⅰ,Ⅱ and Ⅲ,and height of the mandible Ⅰ were found among the 3 groups(P>0.05).Compared with the control group,the operative group showed shorter height of the mandible Ⅱ and width of the mandible,and the operative and sham-operative groups showed shorter height of the mandible Ⅲ(P<0.05).Conclusion Changes on mandibular height Ⅱ and bilateral width after denervation of masseter muscle are noted and no influence on mandibular length is found.
