Location of related brain activation in internet game addicts: an fMRI study
10.3760/cma.j.issn.1671-8925.2010.02.015
- VernacularTitle:网络游戏成瘾者相关脑区功能定位的fMRI研究
- Author:
Min HUANG
1
;
Ruo-Bing QIAN
;
Xian-Ming FU
;
Chang-Xin WANG
;
Ying LIU
;
Xiao-Peng HANG
;
Chao-Shi NIU
;
Ye-Han WANG
Author Information
1. 安徽医科大学附属安徽省立医院
- Keywords:
Internet game addiction;
Functional magnetic resonance imaging;
Limbic system
- From:
Chinese Journal of Neuromedicine
2010;9(2):167-171
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the functional location of brain regions related to internet game addiction using clue-reaction model and functional magnetic resonance imaging (fMRI). Methods Twenty participants with internet game addiction and 20 control subjects without addiction were tested. They were presented with different internet game videos and the paired common life videos while undergoing fMRI. Questionnaire survey was employed to investigate their emotion changes after watching the game video; the activation data produced by the stimulations were collected through the measurement of blood-oxygen-level dependent signals in the brain. Subtraction algorithm was adopted to analyze the corresponding regions of interest. The activated brain areas stimulated by the internet game videos were determined. Results Compared with the common life video watching, the interact game video watching showed significantly different results of psychological assessments, including emotional states, degree of thirst, degree of liking and wishing to re-watch in the addiction group (P<0.05); while the interact game video watching only had a strong degree of re-watching as compared with the common life video watching in the control group. As compared with the common life videos, internet game videos could induce significantly high activation in the parietal lobe and visual cortex of the temporal lobe of the left brain region in the control group (P<0.05);while significantly activation of all the brain regions, except the nucleus accumbens and the caudate nucleus of the left brain region, was found in the internet game video watching as compared with those in the common life video watching in the addiction group (P<0.05). Conclusion The regions of brain activation of the internet game addiction can be determined by fMRI and these areas may be involved in the generation and maintenance of the internet game addiction.
