Management of epileptic foci in patients with dysembryoplastic neuroepithelial tumor

VernacularTitle:胚胎发育不良性神经上皮肿瘤的致痫灶处理
Author: Shi-Yong LIU ¹ ; Ning AN ; Hui YANG ; Zhi HOU ; Mei-Hua YANG ; Yu-Jia WEI ; Wei ZHANG
Author Information

1. 第三军医大学附属新桥医院
Keywords: Dysembryoplastic neuroepithelial tumor; Intractable epilepsy; Surgery; Malformation in the cortical dysplasia
From: Chinese Journal of Neuromedicine 2010;9(2):153-155
CountryChina
Language:Chinese
Abstract: Objective To investigate the management of drug-resistant epilepsy in patients with dysembryoplastic neuroepithelial tumor (DNT). Methods Surgical experiences of 14 patients with DNT in our hospital were retrospectively reviewed. According to the EeoG during the operation and preoperative evaluation, the epileptic foci were managed when the tumor resection was performed. Results The tumors were cut off completely in all the patients; no radiotherapy or chemotherapy was performed after the operation; no recurrence or metastasis of the tumor was found. Engel Ⅰ outcome (seizure-free) was noted in 11 patients and Engel Ⅱ outcome (rare seizure) was noted in 2; frequent seizure was found in 1 after the first operation and seizure-free was achieved after the resection of epileptic foci around the tumor. Conclusion The DNT should be treated as having malformation in the cortical dysplasia and management of epileptic foci around the tumor shows favorable results in the controlling of epilepsy.