Factors associated with cerebral microbleeds in patients with ischemic stroke
10.3760/cma.j.issn.1671-8925.2010.01.016
- VernacularTitle:缺血性卒中患者脑微出血的相关因素分析
- Author:
Song YANG
1
;
Zhi-Ming ZHOU
;
Zhi-Qiang ZHANG
;
Ning WEI
;
Deng-Yue ZHAI
;
Zhen HONG
;
Hai-Ning GAO
;
Xin-Feng LIU
;
Ge-Lin XU
Author Information
1. 南京大学医学院临床学院(南京军区南京总医院)
- Keywords:
Cerebral microbleeds;
Ischemic stroke;
Grandient-echo T2-weighted MRI;
Microangiopathy
- From:
Chinese Journal of Neuromedicine
2010;9(1):64-67
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and neuroimaging features of cerebral microbleeds(CMBs)in patients with ischemic stroke. Methods MRI,including gradient-echo T2~*-weighted MRI,was performed in 85 patients with acute ischemic stroke.Their clinical information and imaging characteristics were analyzed. Results One hundred and twenty-four CMBs were noted in 26 patients(30.6%)with the number of CMBs ranged from 1 to 16 per patient.CMBs were more frequently presentcd in the cortical-subcortical region and thalamus-basal ganglia than in the cerebellum and brain stem legions.Some CMBs in the brain stem had related neurological symptoms and signs.CMBs,the age of the patient,the number of lacunar infarcts and the white matter changes were correlative(r=0.243,P=0.025;r=0.337,P=0.025;r=0.438,P=0.000).CMBs could be well demonstrated in the gradient-echo T2~*-weighted MRI and some larger ones could be demonstrated in the apin-echo T2~*-weighted MRI and DWI. Conclusion CMBs are the sighs for microangiopathy in the brain with advanced age,mutiple lacunar infartion and leukoaraiosis as its main prognosis factors.
