Diffusion tensor magnetic resonance imaging in traumatic optic neuropathy
10.3760/cma.j.issn.1671-8925.2009.11.010
- VernacularTitle:磁共振扩散张量成像技术在外伤性视神经病中应用研究
- Author:
Qin-Tai YANG
1
;
Yan ZOU
;
Xiao-Chun MENG
;
Bing HU
;
Xian LIU
;
Ge-Hua ZHANG
;
Yuan LI
Author Information
1. 中山大学附属第三医院
- Keywords:
Traumatic optic neuropathy;
Diffusion tensor magnetic resonance imaging;
Diffusion tensor tractography
- From:
Chinese Journal of Neuromedicine
2009;8(11):1119-1122
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of diffusion tensor magnetic resonance imaging (DT-MRI) in evaluating traumatic optic neuropathy. Methods DT-MRI data of bilateral optic nerve were acquired in 6 patients with unilateral traumatic optic neuropathy. Volume One 1.44 and DTV2 softwares were employed to measure the fraction anisotropy (FA) and average apparent diffusion coefficient (ADC), and to self-compare between the injured and intact optic nerves. The architecture of the optic radiation fiber tracts were displayed with the software of diffusion tensor fiber tracking. Results All of the infraorbital segments of optic nerves were well demonstrated, with suboptimal intracanalicular portion in 2 patients. The average FA of intraorbital optic nerve in 6 patients: the injured side was 0.244±0.067 and the uninjured side was 0.452±0.053 (P=0.000);FA of the injured side obviously decreased. The average value of ADC: the injured side was (1.417±0.121)×10<'-3> mm<'2>/s and the uninjured side was (1.087±0.118)×10<'3> mm<'2>/s (P=0.003);the value of ADC of the injured side obviously increased. Statistically significant differences were noted between the injured side and the uninjured side. The spacial integralities and connected situations of the nerves could be obtained in 4 patients with significant differences between the injured and the uninjured sides. Conclusion DT-MRI can provide useful pathological information in evaluating traumatic optic neuropathy.
