Correlation between impaired glucose tolerance and carotid atberomatous plaque in patients with acute cerebral infarction
10.3760/cma.j.issn.1671-8925.2009.09.015
- VernacularTitle:急性脑梗死患者糖耐量减低与颈动脉硬化的相关研究
- Author:
Guang-Lun ZENG
1
;
Cheng-Guo ZHANG
;
Guo-De LI
;
Guo-Huo ZHANG
;
Tao LIU
;
Jian XIE
;
Yan SHAO
;
Shao-Hui LUO
;
Wei-Ying PENG
Author Information
1. 广东省佛山市第一人民医院
- Keywords:
Cerebral infarction;
Diabetes mellitus;
Impaired glucose tolerance;
Carotid atheroselerosis
- From:
Chinese Journal of Neuromedicine
2009;8(9):920-922
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between impaired glucose tolerance(IGT)and carotid atheromatous plague in patients with acute cerebral infarction and analyze the risk factors for plaque formation.Methods The 326 patients hospitalized in our department for acute cerebral infarction were divided into diabetes mellitus(DM)group,IGT group and normal glucose tolerance (NGT)group.The clinical features,biochemical indices and results of Doppler ultrasound examination of the carotid artery were compared between the 3 groups.Results The body mass index(BMI),total cholesterol(TC),and low-density lipoprotein cholesterol(LDL-C)of IGT group were markedly higher than those in NGT group(P＜0.05).Both the IGT and DM group showed significantly increased carotid intimal-medial thickness,plaque detection rate and the incidence of carotid scleratheroma in comparison with the NGT group(P＜0.05).Logistic regressive analysis identified age,TC,LDL-C and 2-h postprandial serum glucose as the independent risk factors for carotid scleratheroma.Conclusion In patients with acute cerebral infarction,those having impaired glucose often show obvious carotid scleratheroma with a severity similar to that in the DM patients.
