Clinical and electroencephalographic study of idiopathic nocturnal frontal lobe epllepsy
10.3760/cma.j.issn.1671-8925.2009.04.018
- VernacularTitle:114例特发性夜间额叶癫痫的临床及脑电图研究
- Author:
Xiao-Bing SHI
1
;
Sen-Yang LANG
;
Bao-Lin SHI
;
Cheng XIA
;
Xiang-Qing WANG
Author Information
1. 解放军总医院
- Keywords:
Nocturnal frontal lobe epilepsy;
Clinical phenotype;
Electroencephalogram
- From:
Chinese Journal of Neuromedicine
2009;8(4):395-398
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the characteristics,electroencephalographic(EEG)features,neuroimaging findings,therapeutic effects and prognoses of 114 cases of idiopathic nocturnal frontal lobe epilepsy (NFLE). Methods The clinical data of 114 patients with idiopathic NHLE admitted in the epilepsy outpatient department from June,1999 to January,2007 were collected and analyzed. Results Idiopathic NFLE was clinically characterized by nocturnal clustered,postural or dystonic seizures and complex motor activities.The interictal routine EEG in 22.9% and dynamic EEG in 28% of the cases in wakefuIness and the interictal dynamic EEG in 38% of tbe cases in sleep showed frontal lobe epileptiform discharge,which was found in the EEG during seizure attacks in66.7% of the cases.Drug therapy was effeclive in 79.8% of the cases.with 29.7% of the cases showing complete seizure control. Conclusions Idiopathic NFLE has distinct clinical features wim relatively low rate of EEG abnormality during seizure attack or the interictal period.Frontal lobe epilepsy is more likely to occur in sleep,and sleep EEG is therefore of much importance in the diagnosis of idiopathic NFLE.
