Value of diffusion-weighted magnetic resonance imaging of the thrombi in the cerebral venous sinuses during thrombolytic therapy
10.3760/cma.j.issn.1671-8925.2009.04.016
- VernacularTitle:颅脑静脉窦内血栓磁共振弥散加权成像对溶栓治疗的价值
- Author:
Si-Ping TAN
1
;
Bi-Xian SHEN
;
Wen-Ping MAO
;
Gang LI
;
Bing SUN
Author Information
1. 广东医学院附属深圳南山医院
- Keywords:
Magnetic resonance imaging;
Diffusion-weighted imaging;
Cerebral intrasinus thrombus;
Thrombolytic therapy
- From:
Chinese Journal of Neuromedicine
2009;8(4):388-391
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate diffusion-weighted(DWI)magnetic resonance imaging (MRI) features of the thrombi in patients with cerebral sinus thrombosis(CST),and explore their relation with the recanalization rate alter thrombolytic therapy. Methods The clinical and imaging data were retrospectively analyzed in 14 CST cases,including conventional MRI,FLAIR,DWI and MRV features.The hyperintense signals on DWI at the site ofvenous occlusion were analyzed,and MRV was performed 1-3 months after the thrombolytic therapy to assess the recanalization.The relation between the findings by T1WI,FLAIR and DWI before the thrombolytic therapy and the recanalization rate after the therapy was evaluated.Results Hyperintense signals Was detected in 21 occluded sinuses in 9 patients(41%)with a recellt CVT.Hyperintense signals in the thrombi on the initial MRl were associated with a significantly lowered rate of complete recanalization of the vessel as compared with that among cases without the hyperintense signals(19.0%vs 68.2%,P=0.005). Conclusion The DWI signals of the thrombi in the cerebral venous sinuses can be associated with the progression of the thrombosis,and the presence of hyperintense signals in the occluded cerebral sinuses on the initial DWI may suggest a low rate of sinus recanalization after 1 t0 3 months of thrombolytic therapy.
